About me

My wife Laura, our three sons, daughter, and I live in the Boston, Massachusetts area. I am a Principal with Clarus Ventures, a health care investing firm. I also work with a group called Eventide to promote responsible finance.

I completed a combined MD-PhD program at Harvard Medical School in 2003 (HST Society and the MSTP fellowship). I did my PhD in Harvard's Department of Chemistry & Chemical Biology with Stuart Schreiber. After my MD-PhD, I did my residency and fellowship at the Brigham & Women's Hospital in Boston, Massachusetts. Next I worked at the Broad Institute of Harvard and MIT in Medical & Population Genetics where I did research with David Altshuler and Mark Daly.

Because of an interest in signals and systems theory, I did a Masters at MIT with George Verghese who is in the Department of Electrical Engineering and Computer Science.

In 1995 I completed my undergraduate studies at Caltech where I majored in chemistry. My research advisors were John Abelson and Peter Dervan.

Publications

• Rivas MA et al. Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease. Nature Genetics, 43: 1066-73 (2011). Abstract
• Chiang CW et al. Rapid assessment of genetic ancestry in populations of unknown origin by genome-wide genotyping of pooled samples. PLoS Genetics, 6: e1000866 (2010). Abstract | Full text
• Weiss LA et al. A genome-wide linkage and association scan reveals novel loci for autism. Nature, 461:802-808 (2009). Abstract
• International Schizophrenia Consortium. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature, 460:748-752 (2009). Abstract
• Korn JM, Kuruvilla FG, McCarroll SA, Wysoker A, Nemesh J, Cawley S, Hubbell E, Veitch J, Collins PJ, Darvishi K, Lee C, Nizzari MM, Gabriel SB, Purcell S, Daly MJ, Altshuler D. Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs. Nature Genetics, 40: 1253-60 (2008). Abstract
• McCarroll SA, Kuruvilla FG, Korn JM, Cawley S, Nemesh J, Wysoker A, Shapero MH, de Bakker PI, Maller JB, Kirby A, Elliott AL, Parkin M, Hubbell E, Webster T, Mei R, Veitch J, Collins PJ, Handsaker R, Lincoln S, Nizzari M, Blume J, Jones KW, Rava R, Daly MJ, Gabriel SB, Altshuler D. Integrated detection and population-genetic analysis of SNPs and copy number variation. Nature Genetics, 40: 1166-74 (2008). Abstract
• DIAGRAM consortium. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nature Genetics, 40: 638-45 (2008). Abstract
• Kuruvilla F, Green T, Altshluer D, Daly M, Gabriel S. An evaluation of the Bayesian Robust Linear Modeling using Mahalanobis Distance (BRLMM) Genotyping Algorithm (2006).
• Kuruvilla FG, Shamji AF, Sternson SM, Hergenrother PJ, Schreiber SL. Dissecting glucose signaling using diversity-oriented synthesis and small-molecule microarrays. Nature, 416(6881):653-657 (2002). Abstract | Supplementary material
• Kuruvilla FG, Park PJ, Schreiber SL. Vector algebra in the analysis of genome-wide expression data. Genome Biology, 3(3): research0011.1-0011.11 (2002). Abstract | Full text | Supplementary material
• Kuruvilla FG, Shamji AF, Schreiber SL. Carbon- and nitrogen-quality signaling to translation are mediated by distinct GATA-type transcription factors. Proc Natl Acad Sci USA, 98(13): 7823-7828 (2001). Abstract | Full text
• Shamji AF, Kuruvilla FG, Schreiber SL. Partitioning the transcriptional program induced by rapamycin among the effectors of the Tor proteins. Current Biology, 10(24): 1574-1581 (2000). Abstract | Supplementary material
• Hardwick JS, Kuruvilla FG, Tong JK, Shamji AF, Schreiber SL. Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins. Proc Natl Acad Sci USA, 96(26):14866-70 (1999). Abstract | Full text
• Kuruvilla FG, Schreiber SL. The PIK-related kinases intercept conventional signaling pathways. Chemistry & Biology, 6(5):R129-36 (1999). Abstract
• O'Day CL, Kuruvilla FG (listed as Chavanikamannil F), Abelson J. 18S rRNA processing requires the RNA helicase-like protein Rrp3. Nucleic Acids Research, 24(16):3201-7 (1996). Abstract | Full text

Religion

I have been a practicing Christian for many years. I have a keen interest in biblical interpretation and church history, for the purpose of fostering a strong and vibrant church today. Periods that I have spent significant time on include ante-Nicene Christianity, Reformation and Anabaptist history, and the Great Awakenings of the eighteenth and nineteenth century.

• My personal experience with Christianity
  
• Questions I have wrestled with

In 2003, I compiled and edited a volume of Charles Finney's sermons, entitled True Christianity. It can be purchased from amazon.com by clicking here. I chose to edit this book because, as a Christian, I found Charles Finney's sermons to be the most life-changing I had ever encountered. I hope you do also.

• Recommended reading on Christianity
  
• Recommended audiovisual material on Christianity
  
• Various essays my wife and I have written
  
• Resources on biblical languages

Other

• Healthy eating and plant-based diets
• Some of my favorite quotations