About me

My wife Laura, our three sons, and I live in the Boston, Massachusetts area. I am a Principal with Clarus Ventures, a health care investing firm. I also work with a group called Eventide to promote responsible finance and investing with integrity.

I completed a combined MD-PhD program at Harvard Medical School in 2003 (HST Society and the MSTP fellowship). I did my PhD in Harvard's Department of Chemistry & Chemical Biology with Stuart Schreiber. After my MD-PhD, I did my residency and fellowship at the Brigham & Women's Hospital in Boston, Massachusetts. Next I worked at the Broad Institute of Harvard and MIT in Medical & Population Genetics where I did research with David Altshuler and Mark Daly.

Because of an interest in signals and systems theory, I also completed a Masters at MIT with George Verghese who is in the Department of Electrical Engineering and Computer Science.

In 1995 I completed my undergraduate studies at Caltech where I worked in the laboratories of John Abelson and Peter Dervan.

Publications

• Weiss LA et al. A genome-wide linkage and association scan reveals novel loci for autism. Nature, 461:802-808 (2009) Abstract
• International Schizophrenia Consortium. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature, 460:748-752 (2009) Abstract
• Korn JM, Kuruvilla FG, McCarroll SA, Wysoker A, Nemesh J, Cawley S, Hubbell E, Veitch J, Collins PJ, Darvishi K, Lee C, Nizzari MM, Gabriel SB, Purcell S, Daly MJ, Altshuler D. Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs. Nature Genetics, 40: 1253-60 (2008). Abstract
• McCarroll SA, Kuruvilla FG, Korn JM, Cawley S, Nemesh J, Wysoker A, Shapero MH, de Bakker PI, Maller JB, Kirby A, Elliott AL, Parkin M, Hubbell E, Webster T, Mei R, Veitch J, Collins PJ, Handsaker R, Lincoln S, Nizzari M, Blume J, Jones KW, Rava R, Daly MJ, Gabriel SB, Altshuler D. Integrated detection and population-genetic analysis of SNPs and copy number variation. Nature Genetics, 40: 1166-74 (2008). Abstract
• DIAGRAM consortium. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nature Genetics, 40: 638-45 (2008). Abstract
• Kuruvilla F, Green T, Altshluer D, Daly M, Gabriel S. An evaluation of the Bayesian Robust Linear Modeling using Mahalanobis Distance (BRLMM) Genotyping Algorithm. Online whitepaper (2006).
• Kuruvilla FG, Shamji AF, Sternson SM, Hergenrother PJ, Schreiber SL. Dissecting glucose signaling using diversity-oriented synthesis and small-molecule microarrays. Nature, 416(6881):653-657 (2002). Abstract | Supplementary material
• Kuruvilla FG, Park PJ, Schreiber SL. Vector algebra in the analysis of genome-wide expression data. Genome Biology, 3(3): research0011.1-0011.11 (2002). Abstract | Full text | Supplementary material
• Kuruvilla FG, Shamji AF, Schreiber SL. Carbon- and nitrogen-quality signaling to translation are mediated by distinct GATA-type transcription factors. Proc Natl Acad Sci USA, 98(13): 7823-7828 (2001). Abstract | Full text
• Shamji AF, Kuruvilla FG, Schreiber SL. Partitioning the transcriptional program induced by rapamycin among the effectors of the Tor proteins. Current Biology, 10(24): 1574-1581 (2000). Abstract | Supplementary material
• Hardwick JS, Kuruvilla FG, Tong JK, Shamji AF, Schreiber SL. Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins. Proc Natl Acad Sci USA, 96(26):14866-70 (1999). Abstract | Full text
• Kuruvilla FG, Schreiber SL. The PIK-related kinases intercept conventional signaling pathways. Chemistry & Biology, 6(5):R129-36 (1999). Abstract
• O'Day CL, Kuruvilla FG (listed as Chavanikamannil F), Abelson J. 18S rRNA processing requires the RNA helicase-like protein Rrp3. Nucleic Acids Research, 24(16):3201-7 (1996). Abstract | Full text

• "A Key to Diabetes?" Science 291: 426-427 (2001)

Religion

I have been a practicing Christian for many years. An avid student of the history of religion, my area of particular interest is the history of Christianity in the 1700s and 1800s, especially the figures of John Wesley, George Whitefield, Jonathan Edwards, Nathaniel William Taylor, and Charles Finney. I am also interested in how Christian movements led to the abolition of slavery both in England and in the United States (involving people like Wesley, Finney, and William Wilberforce). I have spoken at a number of churches and campus fellowships on the subject of recovering the historic gospel.

• My personal experience with Christianity
  
• Questions I have wrestled with

In 2003, I compiled and edited a volume of Charles Finney's sermons, entitled True Christianity. It can be purchased from amazon.com by clicking here. I chose to edit this book because, as a Christian, I found Charles Finney's sermons to be the most life-changing I had ever encountered. I hope you do also.

• Recommended reading on Christianity
  
• Recommended audiovisual material on Christianity
  
• Various essays my wife and I have written
  
• Other good Christian resources

Other

I was born and raised in Southern California. During college, I worked part time for World Vision, a humanitarian relief & development agency. My main college activity was involvement with the Caltech Christian Fellowship.

In recent years I have been very involved with the Harvard Graduate School Christian Fellowship and The Society for the Two Tasks, a group that seeks to engage the university on Christian topics. Finally, I work with computers a great deal (click here for my advice on computers, particularly to scientists).

• Healthy eating and plant-based diets
• Quotations I like