Home Page of Finny Kuruvilla
My wife Laura, our five sons, daughter, and I live in the Boston,
I also work with a group
called Eventide in socially
responsible and values-based investing.
Previously, I served as a Principal
with Clarus Ventures, a
health care venture capital firm.
I completed a combined MD-PhD program at Harvard Medical School in
2003 (HST Society and the MSTP fellowship). I did my PhD in Harvard's
Department of Chemistry & Chemical Biology with Stuart Schreiber.
After my MD-PhD, I did my residency and fellowship at the Brigham &
Women's Hospital in Boston, Massachusetts. Next I worked at the Broad
Institute of Harvard and MIT in Medical & Population Genetics where I
did research with David Altshuler and Mark Daly.
Because of an interest in signals and systems theory, I did a Masters
at MIT with George Verghese who is in the Department of Electrical
Engineering and Computer Science.
In 1995 I completed my undergraduate studies at Caltech where I majored in chemistry. My research advisors were John Abelson and Peter Dervan.
I have been a practicing Christian for many years. I fellowship with
called Followers of the
Way. I have a keen interest in biblical interpretation and church
history, for the purpose of fostering a strong and vibrant church
today. Periods that I have spent time on include ante-Nicene
Christianity, Reformation and Anabaptist history, and the Great
Awakenings of the eighteenth and nineteenth century.
For those who call themselves Christians, I wrote a book
called King Jesus Claims His Church that I strongly recommend
reading. It can be purchased from amazon.com by clicking here or
obtained from Scroll Publishing at a cheaper price
In 2003, I compiled and edited a volume of Charles Finney's
sermons, entitled True Christianity. It can be purchased from
amazon.com by clicking here.
- Rivas MA et al. Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease. Nature Genetics, 43: 1066-73 (2011). Abstract
- Chiang CW et al. Rapid assessment of genetic ancestry in
populations of unknown origin by genome-wide genotyping of pooled
samples. PLoS Genetics, 6: e1000866 (2010). Abstract | Full text
- Weiss LA et al. A genome-wide linkage and association scan
reveals novel loci for autism. Nature, 461:802-808 (2009). Abstract
- International Schizophrenia Consortium. Common polygenic
variation contributes to risk of schizophrenia and bipolar disorder.
Nature, 460:748-752 (2009).
- Korn JM, Kuruvilla FG, McCarroll SA, Wysoker A, Nemesh J, Cawley
S, Hubbell E, Veitch J, Collins PJ, Darvishi K, Lee C, Nizzari MM,
Gabriel SB, Purcell S, Daly MJ, Altshuler D. Integrated genotype
calling and association analysis of SNPs, common copy number
polymorphisms and rare CNVs. Nature Genetics, 40:
1253-60 (2008). Abstract
- McCarroll SA, Kuruvilla FG, Korn JM, Cawley S, Nemesh J, Wysoker
A, Shapero MH, de Bakker PI, Maller JB, Kirby A, Elliott AL, Parkin M,
Hubbell E, Webster T, Mei R, Veitch J, Collins PJ, Handsaker R,
Lincoln S, Nizzari M, Blume J, Jones KW, Rava R, Daly MJ, Gabriel SB,
Altshuler D. Integrated detection and population-genetic analysis of
SNPs and copy number variation. Nature Genetics, 40:
1166-74 (2008). Abstract
- DIAGRAM consortium. Meta-analysis of genome-wide association data
and large-scale replication identifies additional susceptibility loci
for type 2 diabetes. Nature Genetics, 40: 638-45
- Kuruvilla F, Green T, Altshluer D, Daly M, Gabriel S. An evaluation
of the Bayesian Robust Linear Modeling using Mahalanobis Distance
(BRLMM) Genotyping Algorithm (2006).
Kuruvilla FG, Shamji AF, Sternson SM, Hergenrother PJ, Schreiber SL.
Dissecting glucose signaling using diversity-oriented synthesis and
small-molecule microarrays. Nature, 416(6881):653-657 (2002).
Kuruvilla FG, Park PJ, Schreiber SL.
Vector algebra in the analysis of genome-wide expression data.
Genome Biology, 3(3): research0011.1-0011.11 (2002).
Full text |
Kuruvilla FG, Shamji AF, Schreiber SL.
Carbon- and nitrogen-quality signaling to translation are mediated by
distinct GATA-type transcription factors. Proc Natl Acad Sci USA,
98(13): 7823-7828 (2001).
Abstract | Full text
Shamji AF, Kuruvilla FG, Schreiber SL.
Partitioning the transcriptional program induced by rapamycin among
the effectors of the Tor proteins.
Current Biology, 10(24): 1574-1581 (2000).
Hardwick JS, Kuruvilla FG, Tong JK, Shamji AF, Schreiber SL.
Rapamycin-modulated transcription defines the subset of nutrient-sensitive
signaling pathways directly controlled by the Tor proteins.
Proc Natl Acad Sci USA, 96(26):14866-70 (1999).
Kuruvilla FG, Schreiber SL.
The PIK-related kinases intercept conventional signaling pathways.
Chemistry & Biology, 6(5):R129-36 (1999).
O'Day CL, Kuruvilla FG (listed as Chavanikamannil F), Abelson J.
18S rRNA processing requires the RNA helicase-like protein Rrp3.
Nucleic Acids Research, 24(16):3201-7 (1996).
I also work with the Society
for the Two Tasks and the New England Christian Education